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| Product Name | DNMT3A, Active |
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| Description | Full Length. MW: ~162 kDa. Description: Recombinant full-length human DNMT3A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: DNMT3A: DNA (cytosine-5-)-methyltransferase 3 alpha plays important role in genomic imprinting and X chromosome inactivation and is essential for mammalian development. DNMT3A appears to function as a de novo methyltrabsferase, since it can methylate unmethylated and hemimethylated DNA with equal efficiencies (1). DNM |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha, mRNA; DNA (cytosine-5)-methyltransferase 3A; DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase 3 alpha; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIA] |
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| Gene, Accession, CAS # | DNMT3A, Gene ID: 1788, Accession: BC043617 |
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| Catalog # | MBS515490 |
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| Order / More Info | DNMT3A, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Yanagisawa, Y. et al: The human DNA methyltransferases DNMT3A and DNMT3B have two types of promoters with different CpG contents. Biochim. Biophys. Acta 1577: 457-465, 2002. 2. Okano, M. et al: DNA methyltransferase Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257, 1999. |
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