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| Product Name | Hepcidin, pro, Human, Control Peptide |
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| Description | Highly purified. An 11aa peptide sequence from the N-terminus of mouse Pro-HEPC. Sequences is 91% conserved in rat and 63% in human pro-HEPC. This sequence is removed from the mature 20-25 secreted forms of HEPC, so antibodies will not react with the secreted forms of HEPC. Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are almost exclusively produced in liver. Human hepcidin is produced from 84-aa precursor, including a putative 24-aa signal peptide. The signal peptide is cleaved to produce pro-HEPC, which is further processed to generate the mature secreted form of hepcidin (C-terminal 20, 22 or 25-aa HEPC). In humans, 20-aa and 25-aa appears to be the major HEPC secreted peptides with antimicrobial activities. The three secreted HEPC alternatively spliced HEPC peptides differ at the |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | Hepcidin, pro, Human, Control Peptide (Pro Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H2009-01A |
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| Order / More Info | Hepcidin, pro, Human, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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