| 产品详情 |
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| Product Name | Hepcidin, pro, Human, Control Peptide |
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| Description | Highly purified. An 11-aa peptide sequence from the N-terminus (after the signal peptide) of human Pro-HEPC. 63% conserved in mouse/rat pro-HEPC Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are almost exclusively produced in liver. Human hepcidin is produced from 84-aa precursor, including a putative 24-aa signal peptide. The signal peptide is cleaved to produce pro-HEPC, which is further processed to generate the mature secreted form of hepcidin (C-terminal 20, 22 or 25-aa HEPC). In humans, 20-aa and 25-aa appears to be the major HEPC secreted peptides with antimicrobial activities. The three secreted HEPC alternatively spliced HEPC peptides differ at the N-terminus. The link between hepcidins and iron metabolism is that hepcidin expression is abolished in mice exhibiting iron-overl |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | Hepcidin, pro, Human, Control Peptide (Pro Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide) Control Peptide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H2009-02B |
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| Order / More Info | Hepcidin, pro, Human, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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