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| Product Name | RAMP2, Human, Control Peptide (Receptor Activity Modifying Protein2) |
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| Description | Highly purified. Control Peptide for R1060-05B and R1060-05. A 20aa Peptide mapping at the middle and a 9 aa peptide mapping near the C-terminus of human RAMP2. The calcitonin family peptides probably act through G-protein coupled membrane receptors. The gene for calcitonin receptors has been cloned. It is homologous to GPCRs in family B which typically recognizes regulatory peptides (secretin, glucagons, VIP). Recently, a homolog of calcitonin receptor, CRLR (calcitonin-receptor-like receptor human 461 aa; rat/mouse 463 aa) was identified. CRLR has 55% homology with calcitonin receptor. It is now shown that CRLR can function as either a CGRP receptor or an ADM receptor, depending upon which members of a new family of proteins called receptor activity modifying proteins (RAMP1-3) are expressed. RAMPs1-3 contains an N-terminal signal peptide, an extracellular N-terminus, a single transmembrane domain near the C-terminus, and cytoplasmic C-terminus. RAMP1-3 displays 31% identity. RAMPS |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | R1060-05A |
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| Order / More Info | RAMP2, Human, Control Peptide (Receptor Activity Modifying Protein2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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