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| Product Name | Nogo Inhibitory Peptide, Rat (Nogo-P4) |
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| Description | Purified by HPLC (mo. Wt 2885, purity ≥90-96%. A 25-aa inhibitory peptide sequence derived from the 66aa active domain; sufficient to produce core inhibitory properties. Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrowafter injury. However, the CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyses. Most recently an inhibitory myelin protein, Nogo (Neurite outgrowth), has been cloned and characterized. It may help block the regeneration of the CNS. Nogo is the 4th member of reticulon (Rtn) family. There are three alternative isoforms of Nogo, designated Nogo-A (full length human protein 1192 aa; calculated mol wt 135kD; rat 1163 aa), an intermediate form Nogo-B (373 aa; ~37 K, lacks 186-1004 aa within the extracellular domain), and a shorter form Nogo-C (199 aa; ~25 K, similar to rat vp20 and foocen-s; lacks 186-1004 aa but which has a smaller, alternative N-term |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2116-10 |
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| Order / More Info | Nogo Inhibitory Peptide, Rat (Nogo-P4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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