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| Product Name | Nogo 66 Receptor-Fc Protein, Recombinant, Human, Western Blot Positive Control |
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| Description | Purity ≥ 95%. Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrow after injury. However, the CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyses. Most recently an inhibitory myelin protein, Nogo (Neurite outgrowth), has been cloned and characterized. It may help block the regeneration of the CNS. Nogo is the 4th member of reticulon (Rtn) family. There are three alternative isoforms of Nogo, designated Nogo-A (full length), an intermediate form Nogo-B (373 aa; ~37 K, lacks 186-1004 aa within the extracellular domain), and a shorter form Nogo-C (199 aa; ~25 K, similar to rat vp20 and foocen-s; lacks 186-1004 aa but which has a smaller, alternative N-terminal domain). A 66-aa hydrophilic region of Nogo (Nogo-66), located between the two TM domains, has the most inhibitory properties of Nogo. In contrast to Nogo, Rtn 1, -2, and 3 do not inhibit axonal regeneration. T |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Nogo 66 Receptor-Fc Protein, Recombinant, Human, Western Blot Positive Control (Ngr, Ngr-Fc Protein) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2116-95F |
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| Order / More Info | Nogo 66 Receptor-Fc Protein, Recombinant, Human, Western Blot Positive Control from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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