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| Product Name | Nogo Receptor 3, Human, Control Peptide (Ngr3, NgRH2) |
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| Description | Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrow after injury. However, the CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyses. Most recently an inhibitory myelin protein, Nogo (Neurite outgrowth), has been cloned and characterized. It may help block the regeneration of the CNS. Recently, a brain specific leucine-rich-repeat protein with high affinity for soluble Nogo-66, termed Nogo receptor (Ngr) has been cloned and characterized. Cleavage of Ngr from the axonal surface renders neurons insensitive to Nogo-66. Ngr expression is sufficient to impart Nogo-66 axonal inhibition to unresponsive neurons. Ngr is expressed in brain and lower levels are also detected in hear and kidney but not in other peripheral tissues. Additional proteins homologous to Ngr have now been identified and designated NGR2 or NgRH1 (nogo-66 receptor homolog-1; human and rat 420 aa; chro |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2116-98B |
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| Order / More Info | Nogo Receptor 3, Human, Control Peptide (Ngr3, NgRH2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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