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| Product Name | PLOD2, GST-Tag, Recombinant (LH2, TLH, Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2) |
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| Description | Lysate. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Source: Partial length protein corresponding to of PLOD2, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~44kD |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | PLOD2, Gene ID: 5352, Accession: NP_000926.2, SwissProt: O00469 |
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| Catalog # | 500897 |
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| Order / More Info | PLOD2, GST-Tag, Recombinant (LH2, TLH, Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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