| 产品详情 |
| Edit |   |
|---|
| Product Name | SB-3CT |
|---|
| Description | Purity >95%. SB-3CT is a selective, mechanism-based inhibitor of the gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9 (Ki s = 28 and 400 nM, respectively). First pass metabolism of SB-3CT in vivo produces a monohydroxylated metabolite that has greater inhibitory activity (Ki s = 6 and 160 nM for MMP-2 and MMP-9, respectively). Both SB-3CT and its active metabolite can cross the blood-brain barrier and have utility in diseases of the central nervous system, such as stroke and traumatic brain injury. SB-3CT may have applications in other pathologies involving gelatinases, including cancer, cardiovascular diseases, and inflammation. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane, Matrix Metalloproteinase-2/9 Inhibitor IV, MMP-2/MMP-9 Inhibitor IV |
|---|
| Gene, Accession, CAS # | CAS: 292605-14-2 |
|---|
| Catalog # | LS-H9848 |
|---|
| Price | |
|---|
| Order / More Info | SB-3CT from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|