Edit |   |
Antigenic Specificity | p53(S376) |
Clone | 7C9 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | p53(S376) (7C9) Monoclonal Antibody. • Target Background: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex |
Immunogen | Synthetic peptide derived from human p53(S376), around 350-400aa (phospho S376). |
Other Names | Phosphorylated, phospho-P53; BCC7; LFS1; TRP53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53 |
Gene, Accession # | Gene ID: 7157, SwissProt: P04637 |
Catalog # | bsm-52181R |
Price | |
Order / More Info | p53(S376) Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |