| 产品详情 |
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| Antigenic Specificity | Bonzo/CXCR6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 6(CXCR6) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins. CXCR6(Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo(322-342aa EDNSKTFSASHNVEATSMFQL), different from the related mouse and rat sequences by three amino acids. |
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| Other Names | C-X-C chemokine receptor type 6;CXC-R6;CXCR-6;CDw186;G-protein coupled receptor STRL33;G-protein coupled receptor bonzo;CD186;CXCR6;BONZO, STRL33, TYMSTR; |
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| Gene, Accession # | CXCR6, UniProt: O00574 |
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| Catalog # | PA2082 |
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| Price | |
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| Order / More Info | Bonzo/CXCR6 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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