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| Product Name | Persephin (PSP, Neurotrophic Factor) |
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| Description | Purity ≥ 98% by SDS-PAGE. Endotoxin: ≤ 0.1ng/ug (1EU/ug). Human Persephin (PSP) a novel neurotrophic factor is about 40% identical to GDNF and Neurturin (NTN). Persephin, like GDNF and NTN, promotes the survival of ventral midbrain dopaminergic neurons in culture. It also supports the survival of motor neurons in culture. Recombinant Human Persephin is a homodimeric 20.6kD protein consisting of two identical subunits each containing 96 amino acid residues. Biological Activity : Human Persephin induces RET phosphorylation using a concentration range of 0.1-1.0ng/ml. Human Persephin binds to mammalian GFRa4 with the Kd of 100pM. Other members of the GDNF family (Artemin, GDNF and Neurturin) do not bind to mammalian GFRa4. AA Sequence : ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3355 |
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| Order / More Info | Persephin (PSP, Neurotrophic Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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