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Product Name | Rivastigmine (tartrate) |
Description | A ChE inhibitor that inhibits BChE and AChE (IC50s = 0.037 and 4.15 µM, respectively); increases levels of sAPP and decreases levels of soluble amyloid-β (1-40) and various N-terminal cleavage products in primary embryonic rat neurons undergoing degeneration at 5 and 10 µM; inhibits formation of amyloid plaques in brain sections and increases in AChE, IL-1β, and BACE1 mRNA expression in the cerebral cortex at 1 mg/kg per day in a rat model of Alzheimer's disease induced by AlCl3; inhibits AlCl3-induced increases in escape latency time in the Morris water maze in a rat model of Alzheimer's disease at 1 mg/kg; reverses decreases in time spent in the open arms of an elevated plus maze, exploration time of a novel object in a novel object recognition test, and sucrose intake in a rat model of chronic mild stress at 2 mg/kg |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | Exelon|SDZ-ENA 713 |
Gene, Accession, CAS # | CAS: 129101-54-8 |
Catalog # | 14270-1 |
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Order / More Info | Rivastigmine (tartrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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