| 产品详情 |
| Edit |   |
|---|
| Product Name | WM3540 Non-Viable Cell Pellet (2 x10^6 cells) |
|---|
| Description | Non-viable cell pellet was generated from cell line WM3540. WM3540 is a human metastatic melanoma cell line that displays a pigmented, mesenchymal morphology. This cell line was established from a lymph node metastases of a patient. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses D97H mutation in CDK4 gene and is wild type for N-RAS and c-KIT. WM3540 cells produce xenograft tumors when injected into immunocompromised mice. |
|---|
| Size | 2 mg |
|---|
| Concentration | 2.0 million cells |
|---|
| Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
|---|
| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | WM3540-03-0002 |
|---|
| Price | |
|---|
| Order / More Info | WM3540 Non-Viable Cell Pellet (2 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|