| 产品详情 |
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| Product Name | PPADS (sodium salt) |
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| Description | Purity >95%. P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50 s = 1-2.6 µM), native P2Y2 -like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[2-[4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]diazenyl]-1,3-benzenedisulfonic acid, tetrasodium salt, Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid |
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| Gene, Accession, CAS # | CAS: 192575-19-2 |
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| Catalog # | LS-H9483 |
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| Order / More Info | PPADS (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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