| 产品详情 |
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| Antigenic Specificity | CCL11 |
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| Clone | 16D10A40 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-CCL11 (Eotaxin). CCL11 is a member of the CC chemokine family and was originally identified as a chemoattractant for eosinophils. In response to allergens, CCL11, which participates in a variety of allergic diseases, promotes accumulation of eosinophils. CCL11 production is upregulated in response to several proinflammatory cytokines, such as IL-4, IL-13, TNF-α, and IFN-α, produced by mast cells and Th2 lymphocytes. CCL11 has been reported to stimulate eosinophil release from bone marrow, resulting in an elevated level of circulating eosinophils. In addition, CCL11 facilitates proliferation and metastasis of tumor cells expressing the CCL11 receptor, CCR3. CCL11 has been shown to induce an angiogenic response by CCR3-positive microvascular endothelial cells. |
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| Immunogen | Human CCL11 recombinant protein (Gly24-Pro97) expressed in E. coli |
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| Other Names | Eotaxin-1, small inducible cytokine subfamily A, member 11 (SCYA11) |
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| Gene, Accession # | Gene ID: 6356 |
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| Catalog # | 656701 |
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| Price | |
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| Order / More Info | CCL11 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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