| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Ticam2 |
|---|
| Clone | CBYJT-3127 |
|---|
| Host Species | Recombinant Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2b |
|---|
| Format | unconjugated |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rat Anti-Ticam2 Recombinant Antibody (CBYJT-3127). Provided herein is a Rat monoclonal antibody, which binds to Ticam2 (Toll-Like Receptor Adaptor Molecule 2). The antibody can be used for immunoassay techniques, such as WB. Ticam2 plays a role as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Ticam2 physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. Ticam2 may also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. It is involved in IL-18 signaling and is propos |
|---|
| Immunogen | E. coli-derived recombinant mouse TRAM/TICAM2, Met1-Ala232, Accession # Q8BJQ4 |
|---|
| Other Names | TRAM; Tirp; Trif; TICAM-2; B430113A10 |
|---|
| Gene, Accession # | Gene ID: 225471, UniProt: Q8BJQ4 |
|---|
| Catalog # | CBMAB-T2395-YJ |
|---|
| Price | |
|---|
| Order / More Info | Ticam2 Antibody from CREATIVE BIOLABS |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|