产品详情 |
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Antigenic Specificity | Tlr1 |
Clone | CBYJT-3342 |
Host Species | Recombinant Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat Anti-Tlr1 Recombinant Antibody (CBYJT-3342). Provided herein is a Rat monoclonal antibody, which binds to Tlr1 (Toll-Like Receptor 1). The antibody can be used for immunoassay techniques, such as WB. Tlr1 participates in the innate immune response to microbial agents. It specifically recognizes diacylated and triacylated lipopeptides. Tlr1 cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. It forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Tlr1 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion |
Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse TLR1, Ser25-Asp581, Accession # Q9EPQ1 |
Other Names | toll-like receptor 1; TIL; toll/interleukin-1 receptor-like protein |
Gene, Accession # | Gene ID: 21897, UniProt: Q9EPQ1 |
Catalog # | CBMAB-T2635-YJ |
Price | |
Order / More Info | Tlr1 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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