产品名称 Tlr1 Antibody from CREATIVE BIOLABS
产品货号 CBMAB-T2637-YJ
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE BIOLABS
产品概述
产品详情
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Antigenic SpecificityTlr1
CloneCBYJT-3344
Host SpeciesRecombinant Rat
Reactive Speciesmouse
IsotypeIgG2a, κ
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsFC
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DescriptionRat Anti-Tlr1 Recombinant Antibody (CBYJT-3344). Provided herein is a Rat monoclonal antibody, which binds to Tlr1 (Toll-Like Receptor 1). The antibody can be used for immunoassay techniques, such as FC. Tlr1 participates in the innate immune response to microbial agents. It specifically recognizes diacylated and triacylated lipopeptides. Tlr1 cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. It forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Tlr1 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion
Immunogenn/a
Other Namestoll-like receptor 1; TIL; toll/interleukin-1 receptor-like protein
Gene, Accession #Gene ID: 21897, UniProt: Q9EPQ1
Catalog #CBMAB-T2637-YJ
Price
Order / More InfoTlr1 Antibody from CREATIVE BIOLABS
Product Specific Referencesn/a
产品资料