| 产品详情 |
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| Product Name | Imatinib, Free base |
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| Description | Purity ~99% (HPLC). An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Solubility: DMSO (25mg/ml) EtOH (5mg/ml) Molecular Weight: ~493.6D |
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| Size | 100ug, 1g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 167887 |
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| Price | |
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| Order / More Info | Imatinib, Free base from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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