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| Product Name | G-CSF BioAssay™ ELISA Kit (Human) |
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| Description | G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Other cell types, including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells, can also secrete G-CSF after LPS, IL-1 or TNF-alpha activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. In humans, two distinct cDNA clones for G-CSF, encoding 207 and 204aa precursor proteins, have been isolated. Both proteins have a 30aa signal peptide and have identical amino acid sequences except for a 3aa insertion (deletion) at the 35aa residue from the N-terminus of the mature protein. Human G-CSF is 73% identical at the amino acid level to mouse G-CSF and the two proteins show species cross-reactivity. In vitro, G-CSF stimul |
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| Size | 48 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | G-CSF BioAssay™ ELISA Kit (Human) (Granulocyte colony-stimulating factor, G-CSF, Pluripoietin, INN: Filgrastim, INN: Lenograstim, CSF3, C17orf33, GCSF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 360278 |
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| Order / More Info | G-CSF BioAssay™ ELISA Kit (Human) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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