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| Product Name | OBFC2A, Recombinant, Human, aa1-204, His-SUMO-Tag (SOSS Complex Subunit B2) |
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| Description | Purity ~90% (SDS-PAGE). Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Source: Recombinant protein corresponding to aa1-204 from human NABP1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~38.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nucleic acid-binding protein |
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| Gene, Accession, CAS # | SwissProt: Q96AH0 |
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| Catalog # | 374523 |
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| Order / More Info | OBFC2A, Recombinant, Human, aa1-204, His-SUMO-Tag (SOSS Complex Subunit B2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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