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| Product Name | ITGA2B, Recombinant, Human, aa639-887, His-SUMO-Tag (Integrin alpha-IIb) |
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| Description | Purity ~90% (SDS-PAGE). Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. Source: Recombinant protein corresponding to aa639-887 from human ITGA2B, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~43kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, CD41 |
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| Gene, Accession, CAS # | SwissProt: P08514 |
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| Catalog # | 373872 |
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| Order / More Info | ITGA2B, Recombinant, Human, aa639-887, His-SUMO-Tag (Integrin alpha-IIb) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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