| 产品详情 |
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| Product Name | VO-OHpic (hydrate) |
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| Description | Purity >95%. VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN; IC50 = 35 nM in vitro ). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3 ) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular systolic pressure and heart rate and protects against ischemia/reperfusion-induced myocardial infarction. VO-OHpic also blocks the development of suppressor activity in regulatory T cells activated with indoleamine 2,3-dioxygenase. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-?N1 ,?O2 )[3-(hydroxy-?O)-2-pyridinecarboxylato(2-)-?O2 ]oxo-vanadate(1-), hydrogen, trihydrate |
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| Gene, Accession, CAS # | CAS: 476310-60-8 |
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| Catalog # | LS-H10453 |
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| Price | |
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| Order / More Info | VO-OHpic (hydrate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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