| 产品详情 |
| Edit |   |
|---|
| Product Name | Glutathione Reductase, Recombinant, Human |
|---|
| Description | Purity ~95% (SDS-PAGE). Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG) (1): GSSG + NADPH + H+ 2GSH + NADP+ In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis (2). Source: Recombinant corresponding to aa44-522 with additional 3aa-GSH at N-term, from human Glutathione Reductase, expressed in |
|---|
| Size | 500ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Glutathione Reductase, Recombinant, Human (Glutathione Reductase, Mitochondrial, GR, GRase, GSR, GLUR, GRD1) |
|---|
| Gene, Accession, CAS # | SwissProt: P00390 |
|---|
| Catalog # | G8127-19P |
|---|
| Price | |
|---|
| Order / More Info | Glutathione Reductase, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|