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Antigenic Specificity | Ring Finger Protein 19A (RNF19A) (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. |
Immunogen | RNF19 A antibody was raised using the N terminal of RNF19 corresponding to a region with amino acids IFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVD |
Other Names | RNF19|RNF19A|AA032313|Dorfin|Rnf19|UIP117|Ubce7ip2|XYbp |
Gene, Accession # | Gene ID: 25897,30945 |
Catalog # | ABIN634836 |
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Order / More Info | Ring Finger Protein 19A (RNF19A) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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