产品详情 |
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Antigenic Specificity | CD8A |
Clone | C8/468 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein A/G purified |
Size | 100 µg |
Concentration | n/a |
Applications | FC, IF, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal Antibody to detect CD8A in human samples. CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, an |
Immunogen | Human CD8 recombinant protein |
Other Names | CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain |
Gene, Accession # | Gene ID: 925, Accession: P01732 |
Catalog # | A1570-100 |
Price | |
Order / More Info | CD8A Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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