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Product Name | WM3060 Non-Viable Cell Pellet (Bulk) |
Description | Non-viable cell pellet was generated from cell line WM3060. WM3060 is a metastatic human melanoma cell line established from a metastatic site (left axillary nodes) in a 55-year-old male with level III malignant melanoma. The subject displayed VGP, and RGP with a tumor thickness of 3.0 mm. This cell line was derived from the same patient as the cell lines WM2013, and WM1960. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. This cell line is wild type for BRAF, PTEN, c-KIT, and CDK4. WM3060 cells produce xenograft tumors when injected into immunocompromised mice. |
Size | 1 each |
Concentration | n/a |
Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
Gene, Accession, CAS # | n/a |
Catalog # | WM3060-03-Bulk |
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Order / More Info | WM3060 Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |
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