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| Product Name | KPNA2, 1-529aa, Human, His tag, E Coli |
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| Description | MW: 60.5 kDa (553aa). Purity >90% by SDS-PAGE. Karyopherin alpha2 (KPNA2) is a member of the karyopherin alpha family. This protein plays a key role in the nuclear import of proteins with a classical nuclear localization signal (NLS). KPNA2 bound in vitro specifically and directly to substrates containing either a simple or bipartite NLS motif. It promoted docking of import substrates to the nuclear envelope and together with recombinant human Ran reconstituted complete nuclear protein import. R |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Importin subunit alpha-2; IPOA1; QIP2; SRP1alpha] |
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| Gene, Accession, CAS # | KPNA2, Gene ID: 3838, Accession: AAH05978 |
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| Catalog # | MBS204676 |
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| Order / More Info | KPNA2, 1-529aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Moroianu J., et al. (1995) Proc. Natl. Acad. Sci. u.S.A. 92:6532-6536; Braem C.V., et al. (2002) J. Biol. Chem. 277:19673-19678 |
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