| 产品详情 |
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| Product Name | Wee1 Recombinant protein |
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| Description | MW: ~115 kDa. Recombinant human WEE1 (247-end) was expressed by E. coli cells using an N-terminal GST tag.Scientific Background: WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases that catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase (1). WEE1 is highly expre |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [WEE1hu] |
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| Gene, Accession, CAS # | Wee1, Gene ID: 7465, Accession: NP_003381.1 |
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| Catalog # | MBS515323 |
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| Order / More Info | Wee1 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Heald, R. et.al: Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase. Cell 74: 463-474, 1993. 2. Parker, L. L. et.al: Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science 257: 1955-1957, 1992. |
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