| 产品详情 |
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| Product Name | Casein Kinase II Inhibitor VIII |
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| Description | Purity ~99% (HPLC). A cell-permeable thiazolamide compound that acts as a potent, reversible, and ATP-competitive inhibitor against casein kinase-2/CK2 (IC50=32 and 46nM against CK2a and CK2a', respectively), as well as DYRK1B and FLt-3 (82% and 76% inhibition, respectively, at 30nM), while diplaying reduced or little potency toward other targets in a 70-kinase panel selectivity profile study. Shown to effectively block the proliferation of a variety of cancer cells (IC50=2.6, 1.6, and 2.4uM, in A549, HCT116, and MCF-7 cultures, respectively). Formula: C18H14N2O4S Molecular Weight: 354.4 Solubility: DMSO (50mg/ml) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Casein Kinase II Inhibitor VIII (4-(2-(4-Methoxybenzamido)thiazol-5-yl)benzoic acid, CK2 Inhibitor VIII, DYRK1B Inhibitor, Flt-3 Inhibitor VII) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217252 |
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| Order / More Info | Casein Kinase II Inhibitor VIII from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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