| 产品详情 |
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| Product Name | Lestaurtinib |
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| Description | Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM, respectively). Also inhibits Aurora kinase A and B (IC50 values are 8.1 and 2.3 nM, respectively) and prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo. Purity 99%. MW (observed): 439.46 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one. CEP-701 |
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| Gene, Accession, CAS # | CAS: 111358-88-4 |
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| Catalog # | 3395/1 |
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| Price | |
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| Order / More Info | Lestaurtinib from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21813452, 21926964, 23301855, 24550330, 26619345 |
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| 产品资料 |
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