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| Product Name | AL 34662 |
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| Description | Purity >97%. The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine; 5-HT) is mediated via at least six major 5-HT receptor subtypes, including 5-HT2 AL 34662 is a potent 5-HT2 receptor agonist with ocular hypotensive activity. It binds to the human and rat 5-HT2 receptors in cerebral cortex homogenates with IC50 values of 1.5 and 0.77 nM, respectively. AL 34662 binds to the recombinant human 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 14.5, 8.1, and 3 nM, respectively. In ocular hypertensive cynomolgus monkey eyes, AL 34662 lowered intraocular pressure (IOP) 25% at a dose of 100 ug and 33% at 300 ug (six hours post dose) with minimal side effects. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(2S)-2-aminopropyl]-1H-indazol-6-ol, AL34497 |
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| Gene, Accession, CAS # | CAS: 210580-75-9 |
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| Catalog # | LS-H59 |
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| Price | |
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| Order / More Info | AL 34662 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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