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| Product Name | AKT1, Recombinant, Human, aa1-480, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). AKT1, also known as RAC-alpha serine/threonine-protein kinase, is catalytically inactive in serum- starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Source: Recombinant protein corresponding to aa1-480 from human AKT1, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~56.7kD(488aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AKT1, Recombinant, Human, aa1-480, His-Tag(RAC-alpha serine/threonine-protein Kinase, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA) |
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| Gene, Accession, CAS # | Accession: NP_001014432 |
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| Catalog # | 351071 |
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| Order / More Info | AKT1, Recombinant, Human, aa1-480, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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