| 产品详情 |
| Edit |   |
|---|
| Product Name | PF-573228 |
|---|
| Description | MW: 491.49. Purity ≥98% by HPLC. Background: PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC?? = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC?? of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. |
|---|
| Size | 10 mg, 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone] |
|---|
| Gene, Accession, CAS # | CAS: 869288-64-2 |
|---|
| Catalog # | MBS843219 |
|---|
| Price | |
|---|
| Order / More Info | PF-573228 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|