产品详情 |
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Antigenic Specificity | Estrogen receptor beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, FCM, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Estrogen receptor beta Antibody. • Target Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol |
Immunogen | KLH conjugated synthetic peptide derived from human ER-beta. Immunogen Range: 220-270/530 |
Other Names | Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; ESR2 |
Gene, Accession # | Gene ID: 2100, SwissProt: Q92731 |
Catalog # | bs-0116R |
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Order / More Info | Estrogen receptor beta Antibody from BIOSS ANTIBODIES |
Product Specific References | Fang, M. et al. (2013) Cell Biochem Biophys. PubMed: 23471663 // Wei, Qing, et al.(2015) Lab Invest.95(7):804-16. PubMed: 26006022 // Rarova, et al. (2018) The Journal of Steroid Biochemistry and Molecular Biology. 178:263-271. PubMed: 29307714 |
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