| 产品详情 |
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| Antigenic Specificity | Human ESR2 |
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| Clone | KK10-13 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human ESR2 monoclonal antibody for WB. Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics. |
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| Immunogen | Recombinant Protein |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 2100, UniProt: F1D8N3 |
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| Catalog # | DCABH-2725 |
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| Price | |
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| Order / More Info | Human ESR2 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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