产品详情 |
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Antigenic Specificity | SRY (Sex Determining Region Y)-Box 2 (SOX2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Embryonic stem cells are derived from the inner cell mass of the blastocyst and are unique in their pluripotent capacity and potential for self-renewal. Sox2 is one of a set of transcription factors that are crucial for the maintenance of pluripotency . Sox2, Oct-4, and Nanog cooperate in this network , and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency . Chromatin immunoprecipitation experiments have shown that Sox2 and Oct-4 bind to thousands of gene regulatory sites, highlighting the importance of these transcription factors in early embryonic development . It has recently been shown that Sox2 is amplified in lung and esophageal squamous cell tumors . Synonyms: SOX2,ANOP3,MCOPS3,MGC2413 , |
Immunogen | Recombinant protein of human SOX2 |
Other Names | Qscn6|Qsox|Sox-2|rSOx|ANOP3|MCOPS3|RGD1565646|SRY-box2|Xsox-2|anop3|mcops3|sox-2|lcc|ysb|cb236|wu:fb83g04|wu:fc14d07|zgc:65860|zgc:77389 |
Gene, Accession # | Gene ID: 6657,20674,499593 |
Catalog # | ABIN1684004 |
Price | |
Order / More Info | SRY (Sex Determining Region Y)-Box 2 (SOX2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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