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Antigenic Specificity | SRY (Sex Determining Region Y)-Box 7 (SOX7) (aa 370-388), (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt(see WNT1)/beta-catenin(see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7(370-388aa LISVLADATATYYNSYSVS), identical to the related mouse and rat sequences. |
Other Names | sox7-A|xSox7 |
Gene, Accession # | Gene ID: 83595,20680,290317 |
Catalog # | ABIN1889233 |
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Order / More Info | SRY (Sex Determining Region Y)-Box 7 (SOX7) (aa 370-388), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 15082719, 18819930, 11691915 |
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