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| Product Name | BDNF, Recombinant, Human (Brain-derived Neurotrophic Factor, Abrineurin, OCD1) |
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| Description | Purity ~98% (SDS-PAGE and HPLC). BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247aa polypeptide precursor, which also contains a signal sequence of 18aa residue and a propeptide of 110aa. Recombinant human BDNF is a 27kD homodimer of two 119aa subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical. Manufactured using all non-animal reagents. Source: Recombinant protein corresponding to human BDNF, expressed in E.coli. Biological Activity: Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for t |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149740 |
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| Order / More Info | BDNF, Recombinant, Human (Brain-derived Neurotrophic Factor, Abrineurin, OCD1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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