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| Product Name | BD4, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE, HPLC). Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The Alpha defensins are differentiated from the Beta-defensins by the pairing of their 3 disulfide bonds. Four human Beta-defensins have been identified to date; BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence (for BD-1 a propeptide region). Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta Defensin-4 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 50aa. The BD-4 is purified by proprietary chromatograph |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BD4, Recombinant, Human (Defensin, beta 104, HBD-4, BD-4, Beta-defensin 104, Beta-defensin 4, DEFB-4, DEFB104A, DEFB104, DEFB4, DEFB104B) |
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| Gene, Accession, CAS # | SwissProt: Q8WTQ1 |
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| Catalog # | B0903-26C |
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| Price | |
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| Order / More Info | BD4, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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