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| Product Name | Mouse IL-23 ELISA |
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| Description | Interleukin-23 was found during a genome scan for the IL-6/IL-12 cytokine family. IL-23 protein is a heterodimer, sharing a p40 subunit with IL-12, but having a distinct p19 subunit, which is IL-23 specific. IL-23 uses many of the same signal-transduction components as IL-12, so it binds to IL-12Rbeta1 receptor, but not IL-12Rbeta2. IL-23 plays a role in type 1-polarized T-cell immune responses. Although IL-12 strongly activates naive T-cells, the initial description of IL-23 reported preferential actions on memory T-cells to increase IFN-gamma production and proliferation suggesting an important role for IL-23 in controlling bacterial infections. IL-23 has further been described as a key cytokine controlling inflammation in peripheral tissues. Overexpression of p19 correlates with inflammation in multiple organs and epithelial tissues including skin. IL-23 was shown to be involved in inflammation of the nervous system and autoimmune diseases. Sample Types: cell culture, citrate plasma, serum. Sample Size: 50 µL. Range: 31.3 - 2,000 pg/mL. Sensitivity: 16.0 pg/mL. Time: 4hr 10min |
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| Size | 96 wells |
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| Concentration | n/a |
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| Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 61-I23MS-E01 |
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| Order / More Info | Mouse IL-23 ELISA from ALPCO |
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| Product Specific References | n/a |
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