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| Product Name | CLCF1, Recombinant, Human, aa28-225, His-Tag |
| Description | Purity ~90% (SDS-PAGE). CLCF1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225aa with a 27aa signal peptide, a molecular mass of 22kD in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Source: Recombinant corresponding to aa28-225 from human CLCF1, fused to His-tag, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF |
| Size | 100ug, 500ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CLCF1, Recombinant, Human, aa28-225, His-Tag (Cardiotrophin-like Cytokine Factor 1, B Cell-stimulating Factor 3, BSF-3, Novel Neurotrophin-1, NNT-1, BSF3, CLC, NNT1) |
| Gene, Accession, CAS # | Accession: NP_037378 |
| Catalog # | 29649 |
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| Order / More Info | CLCF1, Recombinant, Human, aa28-225, His-Tag from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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