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| Antigenic Specificity | Slit Homolog 1 (Drosophila) (SLIT1) (aa 487-504) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.Synonyms: KIAA0813 antibody, MEGF 4 antibody, MEGF4 antibody, Multiple epidermal growth factor-like domains 4 antibody |
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| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 487-504 of mouse SLIT-1 protein. |
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| Other Names | SLIT1|slit1|megf4|slil1|slit3|slit-1|Slil1|mKIAA0813|MEGF4|SLIL1|SLIT-1|SLIT3 |
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| Gene, Accession # | Gene ID: 20562 |
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| Catalog # | ABIN129640 |
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| Price | |
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| Order / More Info | Slit Homolog 1 (Drosophila) (SLIT1) (aa 487-504) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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