| 产品详情 |
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| Product Name | STIMA-1 |
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| Description | MW: 172.19. Purity ≥97%. STIMA-1 (SH group-targeting compound that induces massive apoptosis) reactivates mutant p53. STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells. STIMA-1 is shown to covalently modify free thiols on mutant p53 in H1299-His175 cells and fully restore its DNA binding activity to the level seen with wild-type p53; resulting in upregulation of p53-dependent gene |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2-Vinyl-4H-quinazolinol; SH group-targeting compound that induces massive apoptosis] |
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| Gene, Accession, CAS # | CAS: 91634-12-7 |
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| Catalog # | MBS845640 |
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| Order / More Info | STIMA-1 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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