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| Product Name | HIF1AN, aa576-785, Recombinant, Human |
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| Description | Purity ~85% (SDS-PAGE). HIF1A, identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. This protein is a heterodimer composed of HIF-1beta subunit and one of three subunits(HIF-1A, HIF-2A or HIF-3A). The activation of HIF1A is closely associated with a variety of tumors and oncogenic pathways. HIF1A consists of DNA binding domain(DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains(TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains. Source: Recombinant corresponding to aa576-785 of human recombinant HIF1A(576-785) protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSFDQLSPLE SSSASPESAS PQSTVTVFQQ TQIQEPTANA TTTTATTDEL KTVTKDRMED IKILIASPSP THIHKETTSA TSSPYRDTQS RTASPNRAGK GVIEQTEKSH PRSPNVLSVA LSQRTTVPEE ELNPKILALQ NAQRKRKMEH DGSLFQAVGI GTLLQQPDDH AATTSLSWKR VKGCKSSEQN GMEQKTIILI PSDLACRLLG Q Enzyme Activity: |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HIF1AN, aa576-785, Recombinant, Human (Hypoxia Inducible Factor 1 alpha Inhibitor, DKFZp762F1811, Factor Inhibiting HIF1, FIH1, FLJ20615, FLJ22027, Hypoxia Inducible Factor Asparagine Hydroxylase, Prolyl Hydroxylase) |
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| Gene, Accession, CAS # | Accession: NP_001521 |
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| Catalog # | H3848-86 |
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| Order / More Info | HIF1AN, aa576-785, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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