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| Product Name | HIF1AN Recombinant Human |
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| Description | Purity ≥ 90% (SDS-PAGE). Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1α C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1α transactivation domain results in blockage of the HIF1α-p300/CBP interaction and represses transcriptional activity of HIF1α-targeted genes. Recombinant human HIF1AN protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Human, Recombinant, E. coli, 1-349aa AA Sequence: MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNG |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HIF1AN Recombinant Human (Hypoxia Inducible Factor 1 alpha Inhibitor, DKFZp762F1811, Factor Inhibiting HIF1, FIH1, FLJ20615, FLJ22027, Hypoxia Inducible Factor Asparagine Hydroxylase, Prolyl Hydroxylase) |
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| Gene, Accession, CAS # | Accession: NP_060372 |
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| Catalog # | H3848-85A |
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| Order / More Info | HIF1AN Recombinant Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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