| 产品详情 |
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| Product Name | HIF Inhibitor V |
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| Description | Purity ~99% (HPLC). A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1alpha accumulation in a manner similar to LW6 by upregulating Hippel-Lindau tumor suppressor gene product pVHL, but with much higher potency (IC50 = 120nM vs 2.44uM, respectively, against hypoxia-induced HRE reporter activity in HCT116 cells). Shown to suppress HIF-1 target genes expression in HCT116 cultures and inhibit HUVEC tubule formation (effective conc. ≥2uM) under hypoxia conditions. Molar Mass: 530.7 Solubility: DMSO |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HIF Inhibitor V ((E)-3-(3-(4-Adamantan-1-ylphenoxy)acrylamido)benzoic Acid Morpholinoethyl Ester, Hypoxia-Inducible Factor Inhibitor V) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217424 |
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| Order / More Info | HIF Inhibitor V from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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