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| Product Name | POGLUT1, aa1-388, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). O-Glucosyltransferase1 (POGLUT1) is a homologue of Rumi from Drosophila, an endoplasmic reticulum (ER)-retaining glucosyltransferase, that adds glucose to serine residues within the consensus sequence of C1-X-S-X-P-C2 in Notch EGF repeats, thereby regulating cell-fate decisions (1). It is also known as CAP10-like protein (2) and KTELC1 due to the highly conserved CAP10 domain and the presence of an ER-retaining motif, KTEL, at the C-terminus. The human gene is reported to be involved in the pathogenesis of both acute myelogenous and T-acute lymphoblastic leukemias (3). Recently, POGLUT1 has been demonstrated in a phosphatae- coupled glycosyltransferase assay to have hydrolase activity on UDP-Glc (4). Source: Recombinant corresponding to aa1-388 from human POGLUT, fused with 6-His tag at C-terminal, expressed in CHO cells. Molecular Weight: ~44kD Endotoxin Level: ≤1EU/1ug (LAL) Biological Activity: Recombinant corresponding to aa1-388 from human POGLUT CHO cell l |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | POGLUT1, aa1-388, Recombinant, Human (Protein O-glucosyltransferase 1, CAP10-like 46kD Protein, hCLP46, KTEL Motif-containing Protein 1, Myelodysplastic Syndromes Relative Protein, C3orf9, CLP46, KTELC1, MDSRP, MDS010, UNQ490/PRO1006) |
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| Gene, Accession, CAS # | SwissProt: Q8NBL1 |
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| Catalog # | P2815-09 |
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| Order / More Info | POGLUT1, aa1-388, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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