| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Integrin alpha-L (ITGAL) |
|---|
| Clone | M17-4 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a |
|---|
| Format | Protein G purified |
|---|
| Size | 0.1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Functional Studies (Func),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunoprecipitation (IP),Flow Cytometry (FACS) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions. |
|---|
| Immunogen | C57BL/6 mouse splenic secondary cytotoxic T lymphocytes |
|---|
| Other Names | (p180)|Cd11a|LFA-1|LFA-1A|Ly-15|Ly-21|CD11A|LFA1A|CD11a |
|---|
| Gene, Accession # | Gene ID: 16408 |
|---|
| Catalog # | ABIN457403 |
|---|
| Price | |
|---|
| Order / More Info | Integrin alpha-L (ITGAL) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 17928460, 16517703, 16011799, 11526097, 11222371, 6983917 |
|---|
| 产品资料 |
|
|